Михайлова Мария Евгеньевна

Гидродинамические и электрооптические свойства полимеров в растворах, дендримеры, иономеры, конъюгаты, гребнеобразные полимеры, стабилизация наночастиц серебра полимерами в растворах, синтез наночастиц серебра в растворах в присутствии полимеров, гелеобразование в растворах полисахаридов.

Гранты (текущие):

Мультидисциплинарные (in silico, эксперимент и in vitro) исследование пептидных дендримеров и фуллеренов для использования в качестве средств доставки лекарственных препаратов, имеющих собственные антираковые и антиамилоидные свойства

Основные публикации:

1. Mikhailova M.E., Donets A.V., Rogozhin V.B., Mikusheva N.G., Lezova A.A., Lezov A.A., Tsvetkov N.V., Gellan and pullulan hydrogels of different molar mass, Nanobiotechnology Reports (2024) in press.

2. Lezov A.A., Perevyazko I.Yu., Lezova A.A., Rogozhin V.B., Mikusheva N. G., Fetin P. A., Senchukova A. S., Mikhailova M. E., Donets A. V., Vovk M. A., Zorin I.M., Tsvetkov N. V., Graft copolymers of pullulan with side groups of poly(2-oxazoline) in aqueous solutions: a hydrodynamic study , Nanobiotechnology Reports (2024) in press.

3. Nadezhda N. Sheveleva, Petr V. Konarev, Konstantin M. Boyko, Irina I.Tarasenko, Mariya E. Mikhailova,Valeriy V. Bezrodnyi, Oleg V. Shavykin, Igor M. Neelov, Denis A. Markelov. SAXS, DLS, and MD studies of the Rg/Rh ratio for swollen and collapsed dendrimers.// Journal of Chemical Physics (2024) 161(19). DOI: 10.1063/5.0234864

4. Roman A. Shilov, Vadim A. Baigildin, Kristina S. Kisel, Ekaterina E. Galenko, Alexander S. Gubarev, Mariya E. Mikhailova, Olga S. Vezo, Nikolai V. Tsvetkov, Andrey A. Shtyrov, Mikhail N. Ryazantsev, Julia R. Shakirova, Sergey P. Tunik. RAFT Copolymerization of Pt(II) Pincer Complexes With Water-Soluble Polymer as an Efficient Way to Obtain Micellar-Type Nanoparticles With Aggregation-Induced NIR Emission.// Aggregate (2024) 0:e713. https://doi.org/10.1002/agt2.713

5. Sheveleva N. N., Tarasenko I. I., Vovk M. A., Mikhailova M. E., Neelov I. M., Markelov D. A. NMR Studies of Two Lysine Based Dendrimers with Insertion of Similar Histidine-Arginine and Arginine-Histidine Spacers Having Different Properties for Application in Drug Delivery.// International Journal of Molecular Sciences (2023) 24: 949. https://doi.org/10.3390/ijms24020949

6. Nadezhda N. Sheveleva, Valeriy V. Bezrodnyi, Sofia E. Mikhtaniuk, Oleg V. Shavykin, Igor M. Neelov, Irina I. Tarasenko, Mikhail A. Vovk, Mariya E. Mikhailova, Anastasia V. Penkova, and Denis A. Markelov, Local Orientational Mobility of Collapsed Dendrimers. Macromolecules (2021) 54: 11083−11092. DOI: 10.1021/acs.macromol.1c01835

7. A. A. Lezov, P. A. Fetin, A. S. Gubarev, A. A. Lezova, O. S. Vezo, A. S. Senchukova, M. E. Mikhailova, N. G. Mikusheva, I. M. Zorin, N. V. Tsvetkov, Surface active monomers: from micellar solution properties to molecular characteristics. Journal of Polymer Research (2020) 27: 384. DOI: 10.1007/s10965-020-02357-1

8. Senchukova A.S., Mikhailova M.E., Gubarev A.S., Lezov A.A., Lebedeva E.V., Makarov I.A., Zorin I.M., Tsvetkov N.V., Molecular characteristics of polymerized surfactants: influence of introduced crosslinking agent and monomer concentration. Polym Int (2020) 69: 100–109. DOI: 10.1002/pi.5923

9. Sheveleva N.N., Markelov D.A., Vovk M.A., Mikhailova M.E., Tarasenko I.I., Tolstoy P. M., Neelov I.M., Lähderanta E. Lysine-based dendrimer with double arginine residues. RSC Advances, 9 (31), 18018-18026 (2019). doi:10.1039/c9ra02461a

10. Nadezhda N. Sheveleva, Denis A. Markelov, Mikhail A. Vovk, Irina I. Tarasenko, Mariya E. Mikhailova, Maxim Yu Ilyash, Igor M. Neelov and Erkki Lahderanta. Stable Deuterium Labeling of Histidine-Rich Lysine-Based Dendrimers. Molecules, 24, 2481 (2019). doi:10.3390/molecules24132481 https://www.mdpi.com/1420-3049/24/13/2481

11. I. Perevyazko, E. V. Lebedeva, M. P. Petrov, M. E. Mikhailova, N. G. Mikusheva, O. S. Vezo, M. A. Torlopov, I. S. Martakov, P. V. Krivoshapkin, N. V. Tsvetkov, U. S. Schubert. Analytical ultracentrifugation and other techniques in studying highly disperse nano-crystalline cellulose hybrids. Cellulose 26:7159–7173 (2019). doi: 10.1007/s10570-019-02577-9

12. Mariya E. Mikhailova, Anna S. Senchukova, Alexey A. Lezov, Alexander S. Gubarev, Anne -K. Trützschler, Ulrich S. Schubert and Nikolay V. Tsvetkov. Stabilization of Silver Nanoparticles by Cationic Aminoethyl Methacrylate Copolymers in Aqueous Media—Effects of Component Ratios and Molar Masses of Copolymers. Polymers, 11, 1647 (2019). doi:10.3390/polym11101647 https://www.mdpi.com/2073-4360/11/10/1647

13. Alexey Lezov, Alexander Gubarev, Maria Mikhailova, Alexandra Lezova, Nina Mikusheva, Vladimir Kalganov, Marina Dudkina, Andrey Ten’kovtsev, Tatyana Nekrasova, Larisa Andreeva, Natalia Saprykina, Ruslan Smyslov, Yulia Gorshkova, Dmitriy Romanov, Stephanie Höppener, Igor Perevyazko and Nikolay Tsvetkov. Star-Shaped Poly(2-ethyl-2-oxazoline) and Poly(2-isopropyl-2-oxazoline) with Central Thiacalix[4]Arene Fragments: Reduction and Stabilization of Silver Nanoparticles. Polymers, 11, 2006 (2019), doi:10.3390/polym11122006 https://www.mdpi.com/2073-4360/11/12/2006