Перевязко Игорь Юрьевич

Исследования направлены на изучение молекулярных и конформационных свойств синтетических и биологических полимеров; супрамолекулярных полимеров и метал-супрамолекулярных комплексов; cоздание биосовместимых органических и неорганических наночастиц, самоорганизующихся полимерных систем для векторной доставки генетического материала, получение характеристик белков и их ассоциатов.

Основные публикации:

1. Seiwert, J.; Leibig, D.; Kemmer-Jonas, U.; Bauer, M.; Perevyazko, I.; Preis, J.; Frey, H. Hyperbranched Polyols via Copolymerization of 1,2-Butylene Oxide and Glycidol: Comparison of Batch Synthesis and Slow Monomer Addition Macromolecules 2016, 49, (1), 38-47.
2. Perevyazko, I.; Seiwert, J.; Schömer, M.; Frey, H.; Schubert, U. S.; Pavlov, G. M. Hyperbranched Poly(ethylene glycol) Copolymers: Absolute Values of the Molar Mass, Properties in Dilute Solution, and Hydrodynamic Homology Macromolecules 2015, 10.1021/acs.macromol.5b01020
3. Fruhnert, M.; Kretschmer, F.; Geiss, R.; Perevyazko, I.; Cialla-May, D.; Steinert, M.; Janunts, N.; Sivun, D.; Hoeppener, S.; Hager, M. D.; Pertsch, T.; Schubert, U. S.; Rockstuhl, C. Synthesis, Separation, and Hypermethod Characterization of Gold Nanoparticle Dimers Connected by a Rigid Rod Linker The Journal of Physical Chemistry C 2015, doi/10.1021/acs.jpcc.5b04346
4. Sandmann, B.; Happ, B.; Perevyazko, I.; Rudolph, T.; Schacher, F. H.; Hoeppener, S.; Hager, M.; Mansfeld, U.; Moszner, N.; Fischer, U.; Burtscher, P.; Schubert, U. S. Incorporation of Core-shell Particles in Methacrylate based Composites for an Improvement of the Mechanical Properties Polymer Chemistry 2015, doi/10.1039/c4py01544d
5. van Bracht, E.; Raave, R.; Perevyazko, I. Y.; Versteeg, E. M.; Hafmans, T. G.; Schubert, U. S.; Oosterwijk, E.; van Kuppevelt, T. H.; Daamen, W. F. Albumin based lyophilisomes novel protein capsules as drug delivery system. Eur. J. Pharm. Biopharm. 2015, doi.org/10.1016/j.ejpb.2015.04.020
6. Vollrath, A.; Pretzel, D.; Pietsch, C.; Perevyazko, I.; Menzel, R.; Schubert, S.; Pavlov, G. M.; Weiss, D.; Beckert, R.; Schubert, U. S., Preparation, cellular internalization and biocompatibility of highly fluorescent PMMA nanoparticles. Macromol. Rapid Commun. 2013, 33, 1791-1797.
7. Perevyazko, I. Y.; Vollrath, A.; Pietsch, C.; Schubert, S.; Pavlov, G. M.; Schubert, U. S., Nanoprecipitation of poly(methyl methacrylate)-based nanoparticles: Effect of the molar mass and polymer behavior. J. Polym. Sci., Part A: Polym. Chem. 2012, 50, 2906-2913.
8. Perevyazko, I. Y.; Bauer, M.; Pavlov, G. M.; Hoeppener, S.; Schubert, S.; Fischer, D.; Schubert, U. S., Polyelectrolyte complexes of DNA and linear PEI: Formation, composition and properties. Langmuir 2012, 28, 16167-16176.
9. Happ, B.; Pavlov, G. M.; Perevyazko, I.; Hager, M. D.; Winter, A.; Schubert, U. S., Induced charge effect by co(ii) complexation on the conformation of a copolymer containing a bidentate 2-(1,2,3-triazol-4-yl)pyridine chelating unit. Macromol. Chem. Phys. 2012, 213, 1339-1348.
10. Weber, C.; Babiuch, K.; Rogers, S.; Perevyazko, I. Y.; Hoogenboome, R.; Schubert, U. S., Unexpected radical polymerization behavior of oligo(2-ethyl-2-oxazoline) macromonomers Polymer Chemistry 2012, 3, 2976-2985.
11. Perevyazko, I. Y.; Delaney, J. T.; Vollrath, A.; Pavlov, G. M.; Schubert, S.; Schubert, U. S., Examination and optimization of the self-assembly of biocompatible, polymeric nanoparticles by high-throughput nanoprecipitation. Soft Matter 2011, 7, 5030-5035.
12. Pavlov, G. M.; Perevyazko, I. Y.; Okatova, O. V.; Schubert, U. S., Conformation parameters of linear macromolecules from velocity sedimentation and other hydrodynamic methods. Methods 2011, 54, 124-135.
13. Bloksma, M. M.; Weber, C.; Perevyazko, I. Y.; Kuse, A.; Baumgärtel, A.; Vollrath, A.; Hoogenboom, R.; Schubert, U. S., Poly(2-cyclopropyl-2-oxazoline): From rate acceleration by cyclopropyl to thermoresponsive properties. Macromolecules 2011, 44, 4057-4064.
14. Perevyazko, I.; Vollrath, A.; Hornig, S.; Pavlov, G. M.; Schubert, U. S., Characterization of poly(methyl methacrylate) nanoparticles prepared by nanoprecipitation using analytical ultracentrifugation, dynamic light scattering, and scanning electron microscopy. J. Polym. Sci., Part A: Polym. Chem. 2010, 48, 3924-3931.
15. Pavlov, G. M.; Perevyazko, I.; Schubert, U. S., Velocity sedimentation and intrinsic viscosity analysis of polystyrene standards with a wide range of molar masses. Macromol. Chem. Phys. 2010, 211, 1298-1310.
16. Erdmenger, T.; Perevyazko, I.; Vitz, J.; Pavlov, G.; Schubert, U. S., Microwave-assisted synthesis of imidazolium ionenes and their application as humidity absorbers. J. Mater. Chem. 2010, 20, 3583-3585.
17. Kasyanenko, N.; Mukhin, D.; Perevyazko, I., Conformational changes of a DNA molecule induced by metal complexes formed in solution. Polymer Science Series C 2010, 52, 122-133.
18. Kasyanenko, N. A.; Perevyazko, I. Y.; Blokova, M. I.; Zyryanova, R. M. Influence of divalent metal ions on DNA conformational transitions in water-ethanol solution Biophysics 2008, 53, (2), 229-234